Phenotypes Associated with This Genotype

Genotype
MGI:5009342

• Allelic Composition: Gt(ROSA)26Sor^tm1(EYFP)Cos/Gt(ROSA)26Sor⁺; Ilk^tm1Star/Ilk^tm1Star; Tg(Krt1-15-cre/PGR*)22Cot/0
• Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6J * SJL/J

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

homeostasis/metabolism

abnormal wound healing ( J:172933 )

• during wound regeneration, RU486-treated mice exhibit YFP+ cells in the suprabasal layers but not the basal layers unlike in control mice

delayed wound healing ( J:172933 )

• in RU486-treated mice

integument

abnormal hair follicle development ( J:172933 )

• following treatment with RU486, plated YFP+ hair follicle stem cells do not exhibit spreading unlike YFP- cells