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Phenotypes Associated with This Genotype
Genotype
MGI:5006710
Allelic
Composition		 Cdkn1atm1Led/Cdkn1atm1Led
Zbtb17tm1Cksn/Zbtb17tm1Cksn
Commd10Tg(Vav1-icre)A2Kio/Commd10+
Genetic
Background		 B6.Cg-Zbtb17tm1Cksn Cdkn1atm1Led Commd10Tg(Vav1-icre)A2Kio
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Cdkn1atm1Led mutation (1 available); any Cdkn1a mutation (60 available)
Commd10Tg(Vav1-icre)A2Kio mutation (3 available); any Commd10 mutation (24 available)
Zbtb17tm1Cksn mutation (1 available); any Zbtb17 mutation (43 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
immune system
arrested T cell differentiation ( J:170508 )
• double negative to double positive differentiation is blocked unlike in wild-type mice

hematopoietic system
arrested T cell differentiation ( J:170508 )
• double negative to double positive differentiation is blocked unlike in wild-type mice

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
04/16/2024
MGI 6.23 		The Jackson Laboratory