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Phenotypes Associated with This Genotype
Genotype
MGI:4868201
Allelic
Composition		 Dicer1tm1Bdh/Dicer1+
H2az2Tg(Wnt1-cre)11Rth/H2az2+
Genetic
Background		 involves: 129 * C57BL/6 * CBA/J
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Dicer1tm1Bdh mutation (6 available); any Dicer1 mutation (96 available)
H2az2Tg(Wnt1-cre)11Rth mutation (2 available); any H2az2 mutation (25 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
hematopoietic system
abnormal thymus development ( J:166758 )
• thymus development is delayed at E14.5, but by E16.5, the thymus is indistinguishable from wild-type

immune system
abnormal thymus development ( J:166758 )
• thymus development is delayed at E14.5, but by E16.5, the thymus is indistinguishable from wild-type

endocrine/exocrine glands
abnormal thymus development ( J:166758 )
• thymus development is delayed at E14.5, but by E16.5, the thymus is indistinguishable from wild-type

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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Send questions and comments to User Support. 		last database update
01/06/2026
MGI 6.24 		The Jackson Laboratory