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Phenotypes Associated with This Genotype
Genotype
MGI:4839958
Allelic
Composition		 Gt(ROSA)26Sortm7(SMO*/YFP)Amc/Gt(ROSA)26Sor+
H2az2Tg(Wnt1-cre)11Rth/H2az2+
Genetic
Background		 involves: 129S4/SvJae * 129X1/SvJ * C57BL/6 * CBA * Swiss Webster
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Gt(ROSA)26Sortm7(SMO*/YFP)Amc mutation (0 available); any Gt(ROSA)26Sor mutation (1062 available)
H2az2Tg(Wnt1-cre)11Rth mutation (2 available); any H2az2 mutation (25 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
nervous system
abnormal brain development ( J:165962 )
• display severe dorsal CNS overgrowth

craniofacial
abnormal frontonasal prominence morphology ( J:165962 )
• display dysmorphology of the frontonasal processes

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
01/06/2026
MGI 6.24 		The Jackson Laboratory