Phenotypes for a Lyst Tyrp1 MGI:4454432 MGI Mouse

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Phenotypes Associated with This Genotype

Allelic Composition	a/a Lyst^bg/Lyst^bg Tyrp1^b/Tyrp1^b
Genetic Background	involves: C3H/Rl * C57BL/6J

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
a mutation (166 available); any a mutation (468 available)
Lyst^bg mutation (6 available); any Lyst mutation (227 available)
Tyrp1^b mutation (28 available); any Tyrp1 mutation (160 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

pigmentation

abnormal choroid melanin granule morphology ( J:5346 )

• 80% of premelanosomes in the choroid and retina fuse to form giant granules

abnormal retina melanin granule morphology ( J:5346 )

• 80% of premelanosomes in the choroid and retina fuse to form giant granules

vision/eye

abnormal choroid melanin granule morphology ( J:5346 )

• 80% of premelanosomes in the choroid and retina fuse to form giant granules

abnormal retina melanin granule morphology ( J:5346 )

• 80% of premelanosomes in the choroid and retina fuse to form giant granules

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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