Phenotypes for a Lyst Oca2 MGI:4454430 MGI Mouse

About Help FAQ

Phenotypes Associated with This Genotype

Allelic Composition	a/a Lyst^bg/Lyst^bg Oca2^p-J/Oca2^p-J
Genetic Background	involves: C3H/HeJ * C3H/Rl * C57BL/6J

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
a mutation (166 available); any a mutation (468 available)
Lyst^bg mutation (6 available); any Lyst mutation (227 available)
Oca2^p-J mutation (4 available); any Oca2 mutation (70 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

pigmentation

abnormal melanosome morphology ( J:5346 )

• reorganization of fibrillar melanosomes into particulate melanin granules, such that only 35% of melanosomes in adult retina are fibrillar in nature, the rest are particulate

abnormal choroid melanin granule morphology ( J:5346 )

• 2% of premelanosomes in the choroid are fused to form giant granules

vision/eye

abnormal choroid melanin granule morphology ( J:5346 )

• 2% of premelanosomes in the choroid are fused to form giant granules

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 12/30/2025 MGI 6.24