About   Help   FAQ
Phenotypes Associated with This Genotype
Genotype
MGI:4454420
Allelic
Composition		 Sox4tm1Vlf/Sox4tm1Vlf
Tg(Dbh-icre)1Gsc/0
Genetic
Background		 involves: 129S1/Sv * 129X1/SvJ * C57BL/6J
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Sox4tm1Vlf mutation (0 available); any Sox4 mutation (23 available)
Tg(Dbh-icre)1Gsc mutation (0 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
nervous system
abnormal sympathetic ganglion morphology ( J:157923 )
• show mild reductions in size and cell number at E14.5 and are about two thirds the size of wild-type and have reduced cell numbers at E18.5
abnormal nervous system development ( J:157923 )
• expression analysis indicates a transient delay in noradrenergic differentiation in the sympathetic ganglia

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
03/25/2025
MGI 6.24 		The Jackson Laboratory