Phenotypes Associated with This Genotype

Genotype
MGI:4440460

• Allelic Composition: Dag1^tm2Kcam/Dag1^tm2Kcam; Tg(Nes-cre)1Kln/0
• Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * SJL

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

vision/eye

mydriasis ( J:158199 )

• pupils are dilated but responsive to light

anterior iris synechia ( J:158199 )

• synechia of the iris and cornea

corneal opacity ( J:158199 )

• corneal opacities

buphthalmos ( J:158199 )

microphthalmia ( J:158199 )

abnormal rod electrophysiology ( J:158199 )

• the positive scotopic threshold response is significantly reduced

• the b-wave responses are severely attenuated

blindness ( J:158199 )

• in the Morris water maze and visual cliff test