Mouse Genome Informatics
cx
    Msh2tm1Htr/Msh2tm1Htr
Tap1tm1Hpl/Tap1tm1Hpl

involves: 129P2/OlaHsd * FVB
Key:
phenotype observed in females
phenotype observed in males
N normal phenotype
tumorigenesis
• mice that survive beyond 30 weeks exhibit a multitude of tumors types (erythroid, intestine, skin, uterus, mammary gland, lung, intestine, and hereditary nonpolyposis colorectal cancer)
• in mice that survive beyond 30 weeks
• 80% of mice that survive beyond 30 weeks develop Hereditary Nonpolyposis Colon Cancer (HNPCC) tumors
• in mice that survive beyond 30 weeks
• in mice that survive beyond 30 weeks
• in mice that survive beyond 30 weeks

integument
• in mice that survive beyond 30 weeks

Mouse Models of Human Disease
OMIM IDRef(s)
Lynch Syndrome I 120435 J:45433