Phenotypes Associated with This Genotype

Genotype
MGI:4418567

• Allelic Composition: Ehmt2^tm1.1Tara/Ehmt2^tm1.1Tara; Tg(Camk2a-cre)2Gsc/0
• Genetic Background: involves: 129P2/OlaHsd * C57BL/6 * FVB/N

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

nervous system

nervous system phenotype ( J:155739 )

N • the specific neuronal cell architecture in the striatum and the hippocampus was not altered

behavior/neurological

impaired behavioral response to xenobiotic ( J:155739 )

• almost completely lack a preference for sucrose

decreased exploration in new environment ( J:155739 )

• starting around 6-8 weeks of age, in an open field make fewer total arm entries in an elevated plus maze

abnormal liquid preference ( J:155739 )

• almost completely lack a preference for sucrose

decreased anxiety-related response ( J:155739 )

• make more entries into and spend more time in open arms in an elevated plus maze

decreased vertical activity ( J:155739 )

• in a new environment

decreased locomotor activity ( J:155739 )

• in a new environment

growth/size/body

obese ( J:155739 )

• almost doubled their body weight as compared to controls by 5-6 months of age