Phenotypes Associated with This Genotype

Genotype
MGI:4414766

• Allelic Composition: Ltbp4^{dmod1-129T2/SvEmsJ}/Ltbp4^{dmod1-129T2/SvEmsJ}; Sgcg^tm1Mcn/Sgcg^tm1Mcn
• Genetic Background: 129T2.Cg-Ltbp4^{dmod1-129T2/SvEmsJ} Sgcg^tm1Mcn

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

muscle

skeletal muscle fibrosis ( J:155107 )

• Background Sensitivity: null mice on the 129T2/SvEmsJ background have less hydroxyproline content, a reflection of the degree of fibrosis, than null mice on the DBA/2J background

abnormal muscle physiology ( J:155107 )

• Background Sensitivity: null mice on the 129T2/SvEmsJ background have less muscle membrane leakage, as measured by Evans Dye leakage, than null mice on the DBA/2J background

behavior/neurological

increased grip strength ( J:155107 )

• Background Sensitivity: null mice in the 129T2/SvEmsJ background are stronger than null mice in the DBA/2J background