Ltbp4^{dmod1-129T2/SvEmsJ}
QTL Variant Detail

Summary

• QTL variant: Ltbp4^{dmod1-129T2/SvEmsJ}
• Name: latent transforming growth factor beta binding protein 4; 129T2/SvEmsJ
• MGI ID: MGI:4414657
• QTL: Ltbp4 Location: Chr7:27004561-27037117 bp, - strand Genetic Position: Chr7, 15.87 cM

Variant origin

• Strain of Specimen: 129T2/SvEmsJ

Variant description

• Allele Type: QTL
• Mutation: Insertion
• Mutation details: A 36 bp insertion, encoding for 12 amino acids, extends the proline-rich region of the gene. Strains carrying this insertion include: NZO/HlLtJ, BUB/BnJ, MRL/MpJ, CZECHII/E, MSM/Ms, JF1, CD1, PWD/PhJ, 129S1/SvImJ, 129T2/SvEmsJ, BTBR T<+> tf/J , C57BL/6, C57BL/10. (J:155107)

References

• Original: J:155107 Heydemann A, et al., Latent TGF-beta-binding protein 4 modifies muscular dystrophy in mice. J Clin Invest. 2009 Dec;119(12):3703-12
• All: 1 reference(s)