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Phenotypes Associated with This Genotype
Genotype
MGI:4413349
Allelic
Composition		 Rnf2tm1Mvi/Rnf2tm1Mvi
Tg(Nes-cre/ERT2)5-1Kag/0
Genetic
Background		 involves: 129S1/Sv * 129X1/SvJ * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Rnf2tm1Mvi mutation (1 available); any Rnf2 mutation (36 available)
Tg(Nes-cre/ERT2)5-1Kag mutation (1 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
nervous system
abnormal neuron differentiation ( J:154927 )
• following exposure to tamoxifen at E13.5, the late-born/upper-layer neurons in the cortical plate at P6.5 that had been labeled with BrdU at E19.0 is greater than in control Rnf2tm1Mvi homozygotes

cellular
abnormal neuron differentiation ( J:154927 )
• following exposure to tamoxifen at E13.5, the late-born/upper-layer neurons in the cortical plate at P6.5 that had been labeled with BrdU at E19.0 is greater than in control Rnf2tm1Mvi homozygotes

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
04/16/2024
MGI 6.23 		The Jackson Laboratory