Phenotypes for Ldlr Ppara MGI:4367223 MGI Mouse

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Phenotypes Associated with This Genotype

Allelic Composition	Ldlr^tm1Her/Ldlr^tm1Her Ppara^tm1Gonz/Ppara^tm1Gonz
Genetic Background	involves: 129S4/SvJae * 129S7/SvEvBrd * C57BL/6

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Ldlr^tm1Her mutation (21 available); any Ldlr mutation (78 available)
Ppara^tm1Gonz mutation (5 available); any Ppara mutation (46 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

homeostasis/metabolism

homeostasis/metabolism phenotype ( J:84844 )

N	• fasting glucose levels and insulin levels are not increased after dexamethasone treatment

growth/size/body

decreased lean body mass ( J:84844 )

adipose tissue

increased total body fat amount ( J:84844 )

• after dexamethasone treatment

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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