pigmentation
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• the black pigment in the coat is reduced on this background and is described as sepia, reddish-brown or slate-black
• yellow coat pigment in hair behind the ears, surrounding the mammae, and in the perineum is slightly diluted
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• electron microscopy shows reduced numbers of melanosomes in the retinal pigment epithelium, those that are found have abnormal morphology including multilamellar or granular inclusions, and choroidal melanosomes are also often misshapen and less dense than normal and tend to be clumped within multimelanosomal bodies
(J:81444)
• at birth the iris pigment ring is lacking and adults have ruby colored eyes
(J:13122)
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• the number of melanocytes in the retina, ear skin, Harderian gland, are greatly reduced
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• eyes are unpigmented at birth but later, when opened, are a dark ruby color
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vision/eye
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• electron microscopy shows reduced numbers of melanosomes in the retinal pigment epithelium, those that are found have abnormal morphology including multilamellar or granular inclusions, and choroidal melanosomes are also often misshapen and less dense than normal and tend to be clumped within multimelanosomal bodies
(J:81444)
• at birth the iris pigment ring is lacking and adults have ruby colored eyes
(J:13122)
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• eyes are unpigmented at birth but later, when opened, are a dark ruby color
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integument
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• the black pigment in the coat is reduced on this background and is described as sepia, reddish-brown or slate-black
• yellow coat pigment in hair behind the ears, surrounding the mammae, and in the perineum is slightly diluted
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