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Phenotypes Associated with This Genotype
Genotype
MGI:4356152
Allelic
Composition		 Sox17tm1Jaw/Sox17tm1Jaw
Tg(Pdx1-cre)6Tuv/0
Genetic
Background		 involves: 129S6/SvEvTac * FVB/N
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Sox17tm1Jaw mutation (1 available); any Sox17 mutation (29 available)
Tg(Pdx1-cre)6Tuv mutation (3 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
endocrine/exocrine glands
abnormal bile duct development ( J:151981 )
• at E10.5, the biliary primordium is reduced compared to in control mice

liver/biliary system
abnormal bile duct development ( J:151981 )
• at E10.5, the biliary primordium is reduced compared to in control mice

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
01/06/2026
MGI 6.24 		The Jackson Laboratory