Sox17^tm1Jaw
Targeted Allele Detail

Summary

• Symbol: Sox17^tm1Jaw
• Name: SRY (sex determining region Y)-box 17; targeted mutation 1, Jeffrey A Whitsett
• MGI ID: MGI:4356113
• Synonyms: Sox17^flox
• Gene: Sox17 Location: Chr1:4561154-4567577 bp, - strand Genetic Position: Chr1, 1.65 cM
• Alliance: Sox17^tm1Jaw page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:151981
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: 129S6/SvEvTac

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• Mutation details: A loxP site was inserted upstream of exon 3 and an frt flanked neo cassette with a 3' loxP site was inserted downstream of exon 5. (J:151981)

Expression

In Mice Carrying this Mutation:	23 assay results 1 RNA-Seq or microarray experiment(s)
In Structures Affected by this Mutation:	2 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Sox17 Mutation: 28 strains or lines available

References

• Original: J:151981 Spence JR, et al., Sox17 regulates organ lineage segregation of ventral foregut progenitor cells. Dev Cell. 2009 Jul;17(1):62-74
• All: 6 reference(s)