Phenotypes Associated with This Genotype

Genotype
MGI:4356150

• Allelic Composition: Sox17^tm1Jaw/Sox17^tm1Sjm; Tg(Pdx1-cre)6Tuv/0
• Genetic Background: involves: 129S1/Sv * 129S6/SvEvTac * 129X1/SvJ * FVB/N

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

endocrine/exocrine glands

abnormal bile duct development ( J:151981 )

• at E9.5, Ipfl (Pdx1)+ cells are found throughout the liver bud unlike in control mice

• at E10.0, the biliary primordium is absent unlike in control mice

absent gallbladder ( J:151981 )

• at E16.5

liver/biliary system

abnormal bile duct development ( J:151981 )

• at E9.5, Ipfl (Pdx1)+ cells are found throughout the liver bud unlike in control mice

• at E10.0, the biliary primordium is absent unlike in control mice

absent gallbladder ( J:151981 )

• at E16.5