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Phenotypes Associated with This Genotype
Genotype
MGI:4355665
Allelic
Composition		 Atf1tm1Gsc/Atf1tm1Gsc
Creb1tm3Gsc/Creb1tm3Gsc
Tg(Dbh-icre)1Gsc/0
Genetic
Background		 involves: 129 * 129P2/OlaHsd * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Atf1tm1Gsc mutation (1 available); any Atf1 mutation (209 available)
Creb1tm3Gsc mutation (2 available); any Creb1 mutation (59 available)
Tg(Dbh-icre)1Gsc mutation (0 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
nervous system
decreased neuron apoptosis ( J:121244 )
• number of caspase 3-positive (apoptotic) cells is decreased compared to controls in the SCG at E17.5

cellular
decreased neuron apoptosis ( J:121244 )
• number of caspase 3-positive (apoptotic) cells is decreased compared to controls in the SCG at E17.5

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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Send questions and comments to User Support. 		last database update
04/09/2024
MGI 6.23 		The Jackson Laboratory