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Phenotypes Associated with This Genotype
Genotype
MGI:4354766
Allelic
Composition		 Cbltm1Soga/Cbltm1Soga
Tg(Tec-BCR/ABL1)5Hhi/0
Genetic
Background		 involves: C57BL/6 * DBA/2
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Cbltm1Soga mutation (0 available); any Cbl mutation (57 available)
Tg(Tec-BCR/ABL1)5Hhi mutation (0 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
mortality/aging
premature death ( J:151543 )
• all mice die by 41 weeks after birth with accelerated blast crisis compared to in Tg(BCR/ABL1)5Hhi mice

immune system
enlarged lymph nodes ( J:151543 )
• mice exhibit enlarged lymph nodes during blastic crisis with massive infiltrates of immature leukemic blasts

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
04/30/2024
MGI 6.23 		The Jackson Laboratory