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Phenotypes Associated with This Genotype
Genotype
MGI:3850558
Allelic
Composition		 Il13tm1.1Anjm/Il13tm1.1Anjm
Tg(DO11.10)10Dlo/0
Genetic
Background		 involves: 129P2/OlaHsd * BALB/c * C3H * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Il13tm1.1Anjm mutation (0 available); any Il13 mutation (25 available)
Tg(DO11.10)10Dlo mutation (7 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
immune system
abnormal CD4-positive, alpha-beta T cell physiology ( J:91403 )
• Th2 T cells from these mice fail to induce airway hyperresponsive when transferred to immunodeficient hosts
decreased interleukin-13 secretion ( J:91403 )
• lymphocytes fail to produce IL-13

hematopoietic system
abnormal CD4-positive, alpha-beta T cell physiology ( J:91403 )
• Th2 T cells from these mice fail to induce airway hyperresponsive when transferred to immunodeficient hosts

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
01/06/2026
MGI 6.24 		The Jackson Laboratory