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Phenotypes Associated with This Genotype
Genotype
MGI:3843820
Allelic
Composition		 Il6sttm1Thir/Il6sttm1Thir
Rag2tm1Fwa/Rag2tm1Fwa
Genetic
Background		 involves: 129S/SvEv * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Il6sttm1Thir mutation (1 available); any Il6st mutation (84 available)
Rag2tm1Fwa mutation (46 available); any Rag2 mutation (121 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
immune system
immune system phenotype ( J:133059 )
N
• the arthritis observed in Il6sttm1Thir homozygotes is not observed in these mice demonstrating functional lymphocytes are essential for disease

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
03/18/2025
MGI 6.24 		The Jackson Laboratory