Mouse Genome Informatics
cn
    Brca2tm1Brn/Brca2tm1Brn
Trp53tm1Brn/Trp53tm1Brn
Tg(KRT14-cre)8Brn/0

involves: 129P2/OlaHsd * FVB/N
Key:
phenotype observed in females WTSI Wellcome Trust Sanger Institute
phenotype observed in males EuPh Europhenome
N normal phenotype
       
tumorigenesis
• mice develop tumors with a short median latency period of 181 days
• tumors exhibit expansive growth pattern, a high nuclear grade, and a high mitotic index
• mice develop skin carcinomas

integument
• mice develop skin carcinomas

Mouse Models of Human Disease
OMIM IDRef(s)
Breast Cancer 114480 J:73028