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Phenotypes Associated with This Genotype
Genotype
MGI:3829450
Allelic
Composition		 Ptentm2Mak/Ptentm2Mak
Tg(Vil1-cre/ERT2)23Syr/0
Genetic
Background		 involves: 129P2/OlaHsd * C57BL/6 * CBA
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Ptentm2Mak mutation (4 available); any Pten mutation (86 available)
Tg(Vil1-cre/ERT2)23Syr mutation (1 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
digestive/alimentary system
digestive/alimentary phenotype ( J:143082 )
N
• following induction with tamoxifen in utero or in adult mice, crypt-villi architecture and physiology are normal

integument
ruffled hair ( J:143082 )
• when induced with tamoxifen in utero, mice develop a shaggy or ruffled coat

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
01/06/2026
MGI 6.24 		The Jackson Laboratory