Mouse Genome Informatics
cx
    Cdkn2atm1Rdp/Cdkn2a+
X/Tg(Tyr-HRAS)60Lc

involves: 129/Sv * C57BL/6J * CBA/J * FVB/N * SJL
Key:
phenotype observed in females
phenotype observed in males
N normal phenotype
tumorigenesis
• following exposure to UVA and UVB, 2 of 46 mice exhibit uveal melanoma
• following exposure to UVA and UVB, 2 of 46 mice exhibit uveal melanoma

vision/eye
• following exposure to UVA and UVB, only one mouse developed cataracts unlike Cdkn2atm1Rdp/Cdkn2atm1Rdp Tg(Tyr-HRAS)60Lc mice

Mouse Models of Human Disease
OMIM IDRef(s)
Melanoma, Uveal 155720 J:140820