Mouse Genome Informatics
cn
    Pgrtm2(cre)Lyd/Pgr+
Ptentm1Hwu/Ptentm1Hwu

involves: 129S1/Sv * 129S4/SvJae * 129X1/SvJ * C57BL/6
Key:
phenotype observed in females WTSI Wellcome Trust Sanger Institute
phenotype observed in males EuPh Europhenome
N normal phenotype
       
mortality/aging
• impaired survival is seen beginning around 5 months of age

reproductive system
• by P10, luminal and glandular epithelial hyperplasia are seen (J:139053)

tumorigenesis
• hyperplasia progresses to carcinoma by 1 month of age with invasion into the myometrium detected by 3 months of age (J:139053)

Mouse Models of Human Disease
OMIM IDRef(s)
Endometrial Cancer 608089 J:139053