Phenotypes for Cd79a Cd79b MGI:3813551 MGI Mouse

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Phenotypes Associated with This Genotype

Allelic Composition	Cd79a^tm1.1Cgn/Cd79a^tm1.1Cgn Cd79b^tm2.1Mnz/Cd79b^tm2.1Mnz
Genetic Background	involves: 129/Sv * 129P2/OlaHsd * C57BL/6

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Cd79a^tm1.1Cgn mutation (0 available); any Cd79a mutation (26 available)
Cd79b^tm2.1Mnz mutation (0 available); any Cd79b mutation (36 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

immune system

arrested B cell differentiation ( J:71100 )

• B cell development is blocked in the pro-B cell stage at the fraction C'(BP-1⁺HSA^bright step

absent mature B cells ( J:71100 )

• B cells are absent from the periphery

hematopoietic system

arrested B cell differentiation ( J:71100 )

• B cell development is blocked in the pro-B cell stage at the fraction C'(BP-1⁺HSA^bright step

absent mature B cells ( J:71100 )

• B cells are absent from the periphery

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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