About   Help   FAQ
Phenotypes Associated with This Genotype
Genotype
MGI:3797123
Allelic
Composition
Gli3Xt-J/Gli3+
Sox10tm1Weg/Sox10+
Genetic
Background
involves: 129S1/Sv * 129X1/SvJ * C3H/HeJ
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Gli3Xt-J mutation (3 available); any Gli3 mutation (80 available)
Sox10tm1Weg mutation (1 available); any Sox10 mutation (33 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
pigmentation
• mice exhibit an increased penetrance and severity of hypopigmentation compared to Sox10tm1Weg heterozygotes with ventral hypopigmentation that often extends onto the dorsal surface forming a belt in the lumbar region
• mice exhibit ventral hypopigmentation
• mice exhibit an increased penetrance and severity of hypopigmentation compared to Sox10tm1Weg heterozygotes with ventral hypopigmentation that often extends onto the dorsal surface forming a belt in the lumbar region
• mice exhibit more hypopigmentation than in either single heterozygote

integument
• mice exhibit an increased penetrance and severity of hypopigmentation compared to Sox10tm1Weg heterozygotes with ventral hypopigmentation that often extends onto the dorsal surface forming a belt in the lumbar region
• mice exhibit ventral hypopigmentation


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support.
last database update
04/30/2024
MGI 6.23
The Jackson Laboratory