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Phenotypes Associated with This Genotype
Genotype
MGI:3776807
Allelic
Composition
Tcf3tm1Xhsu/Tcf3tm1Xhsu
Tg(Lck-Stat5b*)1Mafa/0
Genetic
Background
involves: 129X1/SvJ * C57BL/6 * FVB/N
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Tcf3tm1Xhsu mutation (0 available); any Tcf3 mutation (48 available)
Tg(Lck-Stat5b*)1Mafa mutation (0 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
immune system
• B cell proliferation is increased
• however, unlike in mice expressing the transgene alone, B cell maturation in bone marrow and thymus is restored

hematopoietic system
• B cell proliferation is increased
• however, unlike in mice expressing the transgene alone, B cell maturation in bone marrow and thymus is restored

cellular
• B cell proliferation is increased
• however, unlike in mice expressing the transgene alone, B cell maturation in bone marrow and thymus is restored


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
01/06/2026
MGI 6.24
The Jackson Laboratory