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Phenotypes Associated with This Genotype
Genotype
MGI:3776056
Allelic
Composition		 Nf1tm1Par/Nf1tm1Tyj
H2az2Tg(Wnt1-cre)11Rth/H2az2+
Genetic
Background		 involves: 129/Sv * C57BL/6 * CBA
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
H2az2Tg(Wnt1-cre)11Rth mutation (2 available); any H2az2 mutation (26 available)
Nf1tm1Par mutation (4 available); any Nf1 mutation (157 available)
Nf1tm1Tyj mutation (3 available); any Nf1 mutation (157 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
embryo
abnormal neural crest cell morphology ( J:131914 )
• increase in the frequency of neural crest stem cells in the sympathetic chain, dorsal root ganglia, and sciatic nerve at E13 but not at E17 to E19

nervous system
abnormal neural crest cell morphology ( J:131914 )
• increase in the frequency of neural crest stem cells in the sympathetic chain, dorsal root ganglia, and sciatic nerve at E13 but not at E17 to E19

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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Send questions and comments to User Support. 		last database update
04/30/2024
MGI 6.23 		The Jackson Laboratory