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Phenotypes Associated with This Genotype
Genotype
MGI:3767793
Allelic
Composition
Nos2tm1Lau/Nos2tm1Lau
Tg(MMTV-PyVT)634Mul/0
Genetic
Background
B6.Cg-Nos2tm1Lau Tg(MMTV-PyVT)634Mul
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Nos2tm1Lau mutation (8 available); any Nos2 mutation (67 available)
Tg(MMTV-PyVT)634Mul mutation (2 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
neoplasm
• Background Sensitivity: moderate rate of growth of tumors after reaching 1 cubic cm relative to FVB mice
• Background Sensitivity: fewer tumors develop than in FVB mice
• slower to develop mammary tumors (J:84218)
• delayed tumor development relative to FVB mice (J:84218)
• Background Sensitivity: delay in palpable tumor development of 3-4 weeks relative to mice on a FVB background (J:121391)
• Background Sensitivity: latency to tumors of 92 days (J:121391)


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/18/2025
MGI 6.24
The Jackson Laboratory