Analysis Tools
hematopoietic system
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• increase in erythroid precursors in the spleen
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• ratio of alpha-globin RNA to beta-globin RNA was reduced in fetal livers, adult spleens and bone marrow, but not in peripheral blood in embryos and adults
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• reduced compared with those in heterozygotes and normal controls
• normal levels of hemoglobin, however under experimentally induced hemolytic anemia condition, level of hemoglobin was lower in homozygous compared to control
• fully viable and fertile
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• reduced compared with those in heterozygotes and normal controls
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