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Phenotypes Associated with This Genotype
Genotype
MGI:3701081
Allelic
Composition		 Ikzf1tm1(Pax5)Mbu/Ikzf1+
Tg(Lck-cre)1Cwi/0
Genetic
Background		 involves: 129P2/OlaHsd * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Ikzf1tm1(Pax5)Mbu mutation (0 available); any Ikzf1 mutation (31 available)
Tg(Lck-cre)1Cwi mutation (3 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
neoplasm
increased T cell derived lymphoma incidence ( J:118111 )
• immature T cell lymphomas develop with shorter latency than in Ightm1(PAX5)Mbu homozygotes

endocrine/exocrine glands
increased T cell derived lymphoma incidence ( J:118111 )
• immature T cell lymphomas develop with shorter latency than in Ightm1(PAX5)Mbu homozygotes

hematopoietic system
increased T cell derived lymphoma incidence ( J:118111 )
• immature T cell lymphomas develop with shorter latency than in Ightm1(PAX5)Mbu homozygotes

immune system
increased T cell derived lymphoma incidence ( J:118111 )
• immature T cell lymphomas develop with shorter latency than in Ightm1(PAX5)Mbu homozygotes

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
01/06/2026
MGI 6.24 		The Jackson Laboratory