Phenotypes for Cd19 Fas MGI:3690552 MGI Mouse

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Phenotypes Associated with This Genotype

Allelic Composition	Cd19^tm1(cre)Cgn/Cd19⁺ Fas^lpr/Fas^tm1Cgn
Genetic Background	involves: 129P2/OlaHsd * C57BL/6 * MRL

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Cd19^tm1(cre)Cgn mutation (12 available); any Cd19 mutation (57 available)
Fas^lpr mutation (39 available); any Fas mutation (83 available)
Fas^tm1Cgn mutation (1 available); any Fas mutation (83 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

immune system

enlarged spleen ( J:114948 )

• 5-fold enlargement

enlarged lymph nodes ( J:114948 )

• 17-fold enlargement in the lymph nodes

• weight of the enlarged lymph nodes is still 200- to 300-fold less than in Fas^tm1.1Cgn Fas^lpr trans-heterozygous mice

hematopoietic system

enlarged spleen ( J:114948 )

• 5-fold enlargement

growth/size/body

enlarged spleen ( J:114948 )

• 5-fold enlargement

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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