Phenotypes for H2 Rag1 Tg(TcraBDC12-4.1)10Jos Tg(TcrbBDC12-4.1)82Gse MGI:3687166 MGI Mouse

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Phenotypes Associated with This Genotype

Allelic Composition	H2^q/H2^q Rag1^tm1Mom/Rag1^tm1Mom Tg(TcraBDC12-4.1)10Jos/0 Tg(TcrbBDC12-4.1)82Gse/0
Genetic Background	involves: 129S7/SvEvBrd * C57BL/6 * FVB * NOD

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
H2^q mutation (5 available); any H2 mutation (280 available)
Rag1^tm1Mom mutation (49 available); any Rag1 mutation (120 available)
Tg(TcraBDC12-4.1)10Jos mutation (2 available)
Tg(TcrbBDC12-4.1)82Gse mutation (2 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

immune system

decreased susceptibility to autoimmune diabetes ( J:111874 )

• O% of mice homozygous for H2^q develop diabetes

digestive/alimentary system

digestive/alimentary phenotype ( J:111874 )

N	• mice do not develop insulitis

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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