Phenotypes for Fgf8 Tbx1 MGI:3641320 MGI Mouse

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Phenotypes Associated with This Genotype

Allelic Composition	Fgf8^tm1.3Mrt/Fgf8⁺ Tbx1^{tm4(cre/Esr1*)Bld}/Tbx1⁺
Genetic Background	involves: 129P2/OlaHsd * 129S7/SvEvBrd

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Fgf8^tm1.3Mrt mutation (1 available); any Fgf8 mutation (18 available)
Tbx1^{tm4(cre/Esr1*)Bld} mutation (1 available); any Tbx1 mutation (34 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

cardiovascular system

abnormal aortic arch morphology ( J:110620 )

• defects are seen in 52, 32, and 63% of fetuses at E18.5 when tamoxifen is administered at E7.5, 8.5 or 9.5 respectively

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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