About   Help   FAQ
Phenotypes Associated with This Genotype
Genotype
MGI:3622472
Allelic
Composition		 Cd8atm1Mak/Cd8atm1Mak
Tgfb1tm1Doe/Tgfb1tm1Doe
Genetic
Background		 involves: 129S2/SvPas * C57BL/6 * CF-1
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Cd8atm1Mak mutation (7 available); any Cd8a mutation (37 available)
Tgfb1tm1Doe mutation (3 available); any Tgfb1 mutation (34 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
mortality/aging
premature death ( J:99033 )
• majority of double mutants die by 35 days of age

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
01/06/2026
MGI 6.24 		The Jackson Laboratory