Phenotypes for Hoxa3 Hoxd3 MGI:3612029 MGI Mouse

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Phenotypes Associated with This Genotype

Allelic Composition	Hoxa3^tm1Mrc/Hoxa3^tm1Mrc Hoxd3^tm1Mrc/Hoxd3^tm1Mrc
Genetic Background	involves: 129S7/SvEvBrd * C57BL/6J

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Hoxa3^tm1Mrc mutation (0 available); any Hoxa3 mutation (26 available)
Hoxd3^tm1Mrc mutation (0 available); any Hoxd3 mutation (13 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

endocrine/exocrine glands

athymia ( J:19447 )

abnormal thyroid gland morphology ( J:46523 )

• pyramidal ventral lobes

persistent ultimobranchial bodies ( J:46523 )

• ultimobranchial bodies, 100% persistent in adults

immune system

athymia ( J:19447 )

embryo

persistent ultimobranchial bodies ( J:46523 )

• ultimobranchial bodies, 100% persistent in adults

hematopoietic system

athymia ( J:19447 )

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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