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Phenotypes Associated with This Genotype
Genotype
MGI:3606460
Allelic
Composition
Ppm1gtm1Dgen/Ppm1g+
Genetic
Background
involves: 129P2/OlaHsd * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Ppm1gtm1Dgen mutation (1 available); any Ppm1g mutation (25 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
nervous system
• exhibit a significant decrease in prepulse inhibition when compared to age- and gender-matched wildtype controls, indicating a stimulus processing deficit that is observed in some schizophrenic patients

Mouse Models of Human Disease
DO ID OMIM ID(s) Ref(s)
schizophrenia DOID:5419 OMIM:181500
J:101679


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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last database update
04/16/2024
MGI 6.23
The Jackson Laboratory