Phenotypes Associated with This Genotype

Genotype
MGI:3606457

• Allelic Composition: Gria4^tm1Dgen/Gria4^tm1Dgen
• Genetic Background: involves: 129P2/OlaHsd * C57BL/6

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

behavior/neurological

abnormal seizure response to pharmacological agent ( J:101679 )

• higher doses of metrazol are needed to induce some seizure stages while lower doses are needed to induce other stages

increased locomotor activity ( J:101679 )

• increase in the total the distance traveled in an open field

increased thermal nociceptive threshold ( J:101679 )

• prolonged latency in hot plate test

nervous system

abnormal seizure response to pharmacological agent ( J:101679 )

• higher doses of metrazol are needed to induce some seizure stages while lower doses are needed to induce other stages