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Phenotypes Associated with This Genotype
Genotype
MGI:3588504
Allelic
Composition		 Gdnftm1Rosl/Gdnf+
Genetic
Background		 involves: 129S2/SvPas
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Gdnftm1Rosl mutation (0 available); any Gdnf mutation (20 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
renal/urinary system
renal hypoplasia ( J:33808 )
• 4 of 26 have renal hypoplasia
absent kidney ( J:122519 )
• 9% kidney agenesis incidence
single kidney ( J:33808 )
• 7 of 26 have unilateral renal agenesis

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
01/06/2026
MGI 6.24 		The Jackson Laboratory