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Phenotypes Associated with This Genotype
Genotype
MGI:3578403
Allelic
Composition		 Jag1tm1Frad/Jag1tm1Frad
Notch1tm1Agt/Notch1tm1Agt
Tg(Mx1-cre)1Cgn/0
Genetic
Background		 involves: 129 * C57BL/6 * CBA
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Jag1tm1Frad mutation (0 available); any Jag1 mutation (78 available)
Notch1tm1Agt mutation (0 available); any Notch1 mutation (116 available)
Tg(Mx1-cre)1Cgn mutation (10 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
hematopoietic system
hematopoietic system phenotype ( J:98129 )
N
• homozygous mutant mice exhibit normal hematopoiesis, including normal hematopoietic stem cell self-renewal and differentiation

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
01/06/2026
MGI 6.24 		The Jackson Laboratory