Mouse Genome Informatics
ht
    Nrg1tm2Zhou/Nrg1+
involves: 129S4/SvJae * C57BL/6
Key:
phenotype observed in females WTSI Wellcome Trust Sanger Institute
phenotype observed in males EuPh Europhenome
N normal phenotype
       
behavior/neurological
• animals are significantly more active than controls in an open field test and in a four arm-cross maze test
• treatment of mice with 1mg/kg clozapine reversed the phenotype

nervous system
• impairment was seen, while normal acoustic startle response was also observed

Mouse Models of Human Disease
OMIM IDRef(s)
Schizophrenia; SCZD 181500 J:81106