Analysis Tools
endocrine/exocrine glands
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• mutant females have underdeveloped nipples
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• nipple size is significantly smaller than in wild-type females as seen on postpartum day 2
• although difference in nipple size is more striking during pregnancy and lactation, this effect is noted even in non-pregnant females
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• all mutant females are unable to nurse their pups despite normal nursing behavior
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reproductive system
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• about 9% of mutant females are unable to deliver pups
• a greater percentage of pups are stillborn to mutant females compared to wild-type females regardless of the genotype of the pups
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respiratory system
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• fibrosis is seen around the vascular bundles and the bronchioles but not in the parenchyma at 1 and 6 months of age
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integument
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• mutant females have underdeveloped nipples
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• nipple size is significantly smaller than in wild-type females as seen on postpartum day 2
• although difference in nipple size is more striking during pregnancy and lactation, this effect is noted even in non-pregnant females
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• all mutant females are unable to nurse their pups despite normal nursing behavior
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