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Phenotypes Associated with This Genotype
Genotype
MGI:2683315
Allelic
Composition
Men1tm1.2Ctre/Men1tm1.2Ctre
Tg(PTH-cre)4167Slib/0
Genetic
Background
Not Specified
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Men1tm1.2Ctre mutation (1 available); any Men1 mutation (39 available)
Tg(PTH-cre)4167Slib mutation (1 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
endocrine/exocrine glands
• enlarged parathyroid glands
• increased number of densely packed and disorganized follicular cells

homeostasis/metabolism
• significant increase in serum calcium level relative to littermates by 9 months of age
• no difference in serum glucose or creatine levels relative to littermates


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/18/2025
MGI 6.24
The Jackson Laboratory