Phenotypes for Apc Hmmr MGI:2682909 MGI Mouse

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Phenotypes Associated with This Genotype

Allelic Composition	Apc^tm1Rak/Apc⁺ Hmmr^tm1Baa/Hmmr^tm1Baa
Genetic Background	involves: 129P2/OlaHsd * C57BL/6

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Apc^tm1Rak mutation (1 available); any Apc mutation (154 available)
Hmmr^tm1Baa mutation (0 available); any Hmmr mutation (47 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

neoplasm

decreased tumor incidence ( J:86065 )

• decreased number of aggressive fibromatosis tumors formed relative to Apc^tm1Rak heterozygotes

• the number of gastrointestinal polyps was not altered relative to Apc^tm1Rak heterozygotes

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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