Phenotypes Associated with This Genotype

Genotype
MGI:2680169

• Allelic Composition: Tgfbr1^tm1.1Karl/Tgfbr1^tm1.1Karl; Tg(Mx1-cre)1Cgn/0
• Genetic Background: involves: 129 * C57BL/6 * CBA

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

hematopoietic system

hematopoietic system phenotype ( J:86262 )

N • normal hematopoiesis and hematopoietic stem cell self renewal and regenerative ability in spite of an increased hematopoietic stem cell proliferative capacity observed in vitro

increased hematopoietic stem cell proliferation ( J:86262 )

• hematopoietic stem cells from polyIC-induced mice show increased proliferation recruitment when cultured as single cells under low stimulatory conditions in vitro

cellular

increased hematopoietic stem cell proliferation ( J:86262 )

• hematopoietic stem cells from polyIC-induced mice show increased proliferation recruitment when cultured as single cells under low stimulatory conditions in vitro