Phenotypes Associated with This Genotype

Genotype
MGI:2651804

• Allelic Composition: Tg(Hba-x-v-Ha-ras)TG.ACLed/0; Wrn^tm1Led/Wrn^tm1Led
• Genetic Background: involves: 129 * FVB/N * Black Swiss

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

neoplasm

increased incidence of tumors by chemical induction ( J:79056 )

• increased skin and fore-stomach papilloma incidence after TPA-treatment

increased papilloma incidence ( J:79056 )

• increased fore-stomach papilloma incident with or without TPA-treatment

• increased skin papilloma incidence after TPA-treatment

growth/size/body

weight loss ( J:79056 )

• dramatic weight loss between 6 and 8 months of age

• weight loss accompanies fore-stomach papilloma development

homeostasis/metabolism

increased incidence of tumors by chemical induction ( J:79056 )

• increased skin and fore-stomach papilloma incidence after TPA-treatment