Phenotypes associated with this allele
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| Find Mice |
Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Scyl1tm1Spel mutation
(0 available);
any
Scyl1 mutation
(21 available)
Tg(Ckmm-cre)5Khn mutation
(4 available)
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behavior/neurological
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N |
• mice exhibit normal gait and motor function
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muscle
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N |
• mice exhibit normal gait and motor function
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nervous system
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N |
• mice exhibit nor signs of neuroinflammation or neurodegeneration
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|
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| Find Mice |
Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Scyl1tm1Spel mutation
(0 available);
any
Scyl1 mutation
(21 available)
Tg(Nes-cre)1Kln mutation
(4 available)
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behavior/neurological
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N |
• unlike Scyl1tm1.1Spel homozygotes, mice do not develop tremors and the majority do not become paralyzed
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• motor dysfunctions develop more slowly and are not as severe as in Scyl1tm1.1Spel homozygotes
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• posterior waddle by 8 weeks
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muscle
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N |
• unlike Scyl1tm1.1Spel homozygotes, mice do not develop massive muscle wasting
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nervous system
growth/size/body
skeleton
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N |
• unlike Scyl1tm1.1Spel homozygotes, mice do not develop flattening of the pelvis
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cardiovascular system
hematopoietic system
immune system
Analysis Tools