Phenotypes associated with this allele

• Allele Symbol: Celsr2^tm1Lex
• Allele Name: targeted mutation 1, Lexicon Genetics
• Allele ID: MGI:5429210
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Celsr2^tm1Lex/Celsr2^tm1Lex	involves: 129S5/SvEvBrd * C57BL/6J	MGI:5429557

Genotype
MGI:5429557

hm1

• Allelic Composition: Celsr2^tm1Lex/Celsr2^tm1Lex
• Genetic Background: involves: 129S5/SvEvBrd * C57BL/6J

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

behavior/neurological

behavior/neurological phenotype ( J:185566 )

N • normal behavior

growth/size/body

growth/size/body region phenotype ( J:185566 )

N • situs inversus was not observed

nervous system

dilated lateral ventricle ( J:185566 )

• 12 of 13 mice exhibit mild to moderate dilation of the lateral ventricle with mild compression of the surrounding neuropil

dilated third ventricle ( J:185566 )

• 12 of 13 mice exhibit mild to moderate dilation of the third ventricle with mild compression of the surrounding neuropil

reproductive system

reproductive system phenotype ( J:185566 )

N • normal fertility

Mouse Models of Human Disease		DO ID	OMIM ID(s)	Ref(s)
hydrocephalus		DOID:10908	OMIM:123155 OMIM:236600 OMIM:236635 OMIM:307000 OMIM:615219	J:185566